Agenda
The Event
In keeping with Oxford Global’s highly successful life sciences series, an expert panel of 45 speakers will present a full conference programme covering the topics outlined below. These topics have been compiled as a result of a comprehensive research process undertaken with over 20 advisory board members including VPs, Directors, Senior Research Fellows and Professors from global pharmaceutical organisations and leading research institutions.
Stream Titles
Protein Purification, Expression & Characterisation
Antibodies
Biotherapeutics
Immunogenicity
Day 1 Stream 1 – Protein Purification, Expression & Characterisation
• Different expression systems
• Difficult proteins
• Cell line cultivation and development
• Vector screening
• Recombinant protein expression
• CHO platforms
• Functional characterisation
• Unfolded proteins
• Cell free systems
• Structural biology
Day 1 Stream 2 – Antibodies
• Antibody engineering
• Bispecific antibodies and other novel constructs
• Anti-body drug conjugates
• Aggregation
• Pharmaceutical properties
• Analytical and regulatory challenges
• Enhancing the potency of antibodies
Day 2 Stream 1 – Biotherapeutics
• Extending half life
• Fab and single chain fragments
• Hybrid proteins
• Receptor modification
• Targeting receptors
• Chemical biology
• Alternative scaffolds
• Protein-protein interaction
• Manufacturability
Day 2 Stream 2 – Immunogenicity
• Controlling immunogenicity
• Early assessment
• Response triggers
• Aggregation
• Predictive algorithms
• New approaches to mitigation and minimisation
